Co-optimization of energy and reserve capacity considering renewable energy unit with uncertainty

This paper proposes a system model for optimal dispatch of the energy and reserve capacity considering uncertain load demand and unsteady power generation. This implicates uncertainty in managing the power demand along with the consideration of utility, user and environmental objectives. The model takes into consideration a day-ahead electricity market that involves the varying power demand bids and generates a required amount of energy in addition with reserve capacity. The lost opportunity cost is also considered and incorporated within the context of expected load not served. Then, the effects of combined and separate dispatching the energy and reserve are investigated. The nonlinear cost curves have been addressed by optimizing the objective function using robust optimization technique. Finally, various cases in accordance with underlying parameters have been considered in order to conduct and evaluate numerical results. Simulation results show the effectiveness of proposed scheduling model in terms of reduced cost and system stability

Artificial intelligence-enabled probabilistic load demand scheduling with dynamic pricing involving renewable resource

Residential demand response is one of the key enabling technologies which plays an important role in managing the load demand of prosumers. However, the load scheduling problem becomes quite challenging due to the involvement of dynamic parameters and renewable energy resources. This work has proposed a bi-level load scheduling mechanism with dynamic electricity pricing integrated with renewable energy and storage system to overcome this problem. The first level involves the formulation of load scheduling and optimization problems as optimal stopping problems with the objective of energy consumption and delay cost minimization. This problem involved the real-time electricity pricing signal, customers load scheduling priority, machine learning (ML) based forecasted load demand, and renewable & storage unit profiles, which is solved using mathematical programming with branch-and-cut & branch-and-bound algorithms. Since the first-level optimization problem is formulated as a stopping problem, the optimal time slots are obtained using a one-step lookahead rule to schedule the load with the ability to handle the uncertainties. The second level is used to further model the load scheduling problem through the dynamic electricity pricing signal. The cost minimization objective function is then solved using the genetic algorithm (GA), where the input parameters are obtained from the first-level optimization solution. Furthermore, the impact of load prioritization in terms of time factor and electricity price is also modeled to allow the end-users to control their load. Analytical and simulation results are conducted using solar-home electricity data, Ausgrid, AUS to validate the proposed model. Results show that the proposed model can handle uncertainties involved in the load scheduling process along with a cost-effective solution in terms of cost and discomfort reduction. Furthermore, the bi-level process ensures cost minimization with end-user satisfaction regarding the dynamic electricity price signal

productivity improvement through time study approach a case study from an apparel manufacturing industry of pakistan

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Functional Role of MicroRNAs in Embryogenesis

This book chapter will provide an overview of the functional role of microRNAs (miRNAs) in embryogenesis. A brief introduction to embryogenesis and emphasis on the importance of miRNAs in gene regulation will be provided. The biogenesis and mechanism of action of miRNAs will be discussed in detail with a focus on the importance of miRNA-mRNA interaction in gene regulation. The chapter will then delve into the role of miRNAs in early embryonic development, including their importance in the establishment of the three germ layers, cell proliferation, differentiation, and apoptosis during embryogenesis. The role of miRNAs in organogenesis and tissue differentiation, specifically the formation of specific organs such as the heart, lung, liver, and brain, will also be discussed. The chapter will conclude by examining the dysregulation of miRNAs in embryonic development and disease, including teratogenicity, developmental disorders, and developmental cancer. The chapter will summarize the functional roles of miRNAs in embryogenesis and will offer future perspectives and potential therapeutic applications of miRNAs in embryonic development and disease

Implementation and evaluation of a social media-based communication strategy to enhance employee engagement: Experiences from a children\u27s hospital, Pakistan

Social media can complement organizational communication strategy which is integral to employee engagement. However, successful case studies which can allow replication are limited. The objective of the study is to describe the design, implementation, and evaluation of a social media-based communication strategy in a tertiary care hospital in Pakistan. The leadership of the pediatric service line developed an intervention plan to engage the employees with the newly reframed vision to improve patient and family experience. An online communication platform-Facebook page-was created for all employees of the pediatric service line. The strategy to influence employees was based on Cialdini\u27s six principles of persuasion. Implementation of the strategy between October 2017 and December 2019 was evaluated for reach, discussion themes, and outcomes using the framework by Murdough (2009). Quantitative indicators included total posts, mean comments, and reactions per post. Posts were qualitatively analyzed with an emergent approach for insights into the discussion. The analysis revealed a total of 9,085 posts, with mean reactions per post of 8.4, mean comments of 7.2, and active viewership by 90% members on average. In terms of post types, photos were the highest (4,779), while videos were the lowest (1,163). Qualitative analysis indicated 54% of the posts were of the theme inspirational and thought provoking, while the greatest engagement was generated on the theme challenges and solution. The authors conclude that the strategy was successfully implemented to maintain active membership, engage employees in meaningful conversations, and have them express intent to execute quality improvement projects

Implementation and Evaluation of a Social Media-Based Communication Strategy to Enhance Employee Engagement: Experiences From a Children's Hospital, Pakistan

Social media can complement organizational communication strategy which is integral to employee engagement. However, successful case studies which can allow replication are limited. The objective of the study is to describe the design, implementation, and evaluation of a social media-based communication strategy in a tertiary care hospital in Pakistan. The leadership of the pediatric service line developed an intervention plan to engage the employees with the newly reframed vision to improve patient and family experience. An online communication platform—Facebook page—was created for all employees of the pediatric service line. The strategy to influence employees was based on Cialdini's six principles of persuasion. Implementation of the strategy between October 2017 and December 2019 was evaluated for reach, discussion themes, and outcomes using the framework by Murdough (2009). Quantitative indicators included total posts, mean comments, and reactions per post. Posts were qualitatively analyzed with an emergent approach for insights into the discussion. The analysis revealed a total of 9,085 posts, with mean reactions per post of 8.4, mean comments of 7.2, and active viewership by 90% members on average. In terms of post types, photos were the highest (4,779), while videos were the lowest (1,163). Qualitative analysis indicated 54% of the posts were of the theme “inspirational and thought provoking,” while the greatest engagement was generated on the theme “challenges and solution.” The authors conclude that the strategy was successfully implemented to maintain active membership, engage employees in meaningful conversations, and have them express intent to execute quality improvement projects.publishedVersio

Frequency and Outcome of Carotid Atheromatous Disease in Patients With Stroke in Pakistan

Background And Purpose: Limited data exist on the frequency and outcome of carotid artery disease in Pakistan. Such information would help guide the usefulness of screening for the condition in this low-middle income health care setting. Methods: A prospective, descriptive study was conducted among 3 large teaching hospitals in Karachi, Pakistan. Patients referred for carotid Doppler ultrasound examination were included if they had experienced a stroke or TIA within the previous month. The severity and morphology of carotid disease were characterized by trained technicians using standardized criteria. Demographic and risk factor data were collected at baseline, and the outcome of Patients was assessed at least 6 months later. Results: A total of 672 Patients underwent bilateral carotid Doppler ultrasound (1344 carotid examinations). The findings revealed 0% to 50% stenosis in 526 (78%), 51% to 69% stenosis in 57 (8%), 70% to 99% stenosis in 82 (12%), and total occlusion in 7 Patients (1%). Potentially surgically correctable disease, defined as 70% to 99% carotid artery stenosis, was present in only 79 (12%) Patients, of whom 47 (60%) were ipsilateral symptomatic, 15 (20%) asymptomatic, and 17 (20%) had status unknown. Outcome information at \u3e= 6 months follow-up was available for 36 of the 47 (76%) surgically correctable and only 4 of these Patients (12%) had undergone surgical or radiological intervention (carotid endarterectomy in 3 Patients and carotid stenting in 1 Patient). Conclusion: The frequency of carotid artery disease of at least moderate severity is very low in Patients with recent stroke or TIA and there is low utilization of high-cost, carotid intervention procedures in Pakistan. These data raise questions regarding the applicability and cost-effectiveness of routine carotid ultrasound screening in our country and similar population in Asia. The local socio-economic and clinical data do not support routine carotid Doppler ultrasound in every Patient with stroke and TIA in Pakistan. Studies are warranted to determine predictors of significant carotid artery stenosis in stroke/TIA Patients of our country to develop reliable stroke guidelines appropriate for local population

A nationwide virtual research education program for medical students in Pakistan: Methodological framework, feasibility testing, and outcomes

Introduction: Equipping young medical trainees with fundamental research skills can be a promising strategy to address the need for professionals who can understand and responsibly communicate evolving scientific evidence during a pandemic. Despite an ardent interest to partake in research, most educational institutions in Pakistan and other low-middle income countries have not yet adopted a comprehensive strategy for research skills education. The authors aimed to design and assess the feasibility of implementing the first nation-wide virtual research workshop for medical students in Pakistan. Methods: The course Beginners Guide to Research, designed as a nation-wide virtual research workshop series, was conducted for medical students across Pakistan in June 2020. Four interactive live workshops took place online on alternate days from June 22nd, 2020, to June 27th, 2020, each lasting 1-2 h. Outcomes included: (i) reach, (ii) efficacy as indexed by pre-post change in score pertaining to knowledge and application of research and (iii) self-rated perceptions about understanding of research on a Likert scale. Results: 3,862 participants enrolled from 41 cities and 123 institutions. Enrolled participants belonged to the following provinces: Sindh (n = 1,852, 48.0%), Punjab (n = 1,767, 45.8%), Khyber Pakhtunkhwa (n = 109, 2.8%), Azad Jammu and Kashmir (n = 84, 2.2%) Balochistan (n = 42, 1.1%). We also saw a few registrations from international students (n = 8, 0.2%). Mean (SD) age of enrolled medical students was 21.1 (2.1) years, 2,453 (63.5%) participants were female and 2,394 (62.0%) were from private-sector medical colleges. Two thousand ninety-three participants participants filled out all four pre-test and post-test forms. The total median knowledge score improved from 39.7 to 60.3% with the highest improvements in concepts of research bioethics and literature search (p \u3c 0.001) with greater change for females compared to males (+20.6 vs. +16.2%, p \u3c 0.001) and private institutions compared to public ones (+16.2 vs. +22.1%, p \u3c 0.001). Conclusion: The overwhelming enrollment and significant improvement in learning outcomes (\u3e50% of baseline) indicate feasibility of a medical student-led research course during a pandemic, highlighting its role in catering to the research needs in the LMICs